Ryze Runes for Top Path 14.21

Recommended Ryze runes for the Top path in patch 14.21, tailored for the current LoL meta.
Ryze
Ryze the Rune Mage
Arcane Mastery Overload Q Rune Prison W Spell Flux E Realm Warp R
D Win rate 50.00% Pick rate 2.22% Ban rate 0.18% KDA 2.30
60% 40%

Keystones

Sorcery Phase Rush Inspiration
66.67% 2 Matches
50.00% Win rate
Sorcery Phase Rush Resolve
33.33% 1 Matches
100.00% Win rate

Ryze runes

50.00% WR (2 Matches)
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
100.00% WR (1 Matches)
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE