Nautilus Runes for Support Path 14.21

Recommended Nautilus runes for the Support path in patch 14.21, tailored for the current LoL meta.
Nautilus
Nautilus the Titan of the Depths
Staggering Blow Dredge Line Q Titan's Wrath W Riptide E Depth Charge R
C Win rate 48.09% Pick rate 6.98% Ban rate 13.56% KDA 2.40
97%

Keystones

Resolve Aftershock Inspiration
55.59% 1616 Matches
49.32% Win rate
Resolve Aftershock Precision
22.94% 667 Matches
48.13% Win rate
Inspiration Glacial Augment Resolve
15.14% 440 Matches
43.41% Win rate
Resolve Aftershock Domination
2.41% 70 Matches
55.71% Win rate
Resolve Aftershock Sorcery
0.89% 26 Matches
46.15% Win rate

Nautilus runes

49.89% WR (936 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
43.79% WR (169 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
42.11% WR (38 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
57.14% WR (28 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
52.63% WR (19 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
48.57% WR (560 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Precision Precision
Press the Attack Lethal Tempo Fleet Footwork Conqueror
Absorb Life Triumph Presence of Mind
Legend: Alacrity Legend: Haste Legend: Bloodline
Coup de Grace Cut Down Last Stand
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
25.00% WR (12 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Precision Precision
Press the Attack Lethal Tempo Fleet Footwork Conqueror
Absorb Life Triumph Presence of Mind
Legend: Alacrity Legend: Haste Legend: Bloodline
Coup de Grace Cut Down Last Stand
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
33.33% WR (9 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Precision Precision
Press the Attack Lethal Tempo Fleet Footwork Conqueror
Absorb Life Triumph Presence of Mind
Legend: Alacrity Legend: Haste Legend: Bloodline
Coup de Grace Cut Down Last Stand
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
60.00% WR (5 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Precision Precision
Press the Attack Lethal Tempo Fleet Footwork Conqueror
Absorb Life Triumph Presence of Mind
Legend: Alacrity Legend: Haste Legend: Bloodline
Coup de Grace Cut Down Last Stand
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
60.00% WR (5 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Precision Precision
Press the Attack Lethal Tempo Fleet Footwork Conqueror
Absorb Life Triumph Presence of Mind
Legend: Alacrity Legend: Haste Legend: Bloodline
Coup de Grace Cut Down Last Stand
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
42.74% WR (365 Matches)
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
50.00% WR (4 Matches)
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
50.00% WR (4 Matches)
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
50.00% WR (4 Matches)
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
33.33% WR (3 Matches)
Inspiration Inspiration
Glacial Augment Unsealed Spellbook First Strike
Hextech Flashtraption Magical Footwear Cash Back
Triple Tonic Time Warp Tonic Biscuit Delivery
Cosmic Insight Approach Velocity Jack Of All Trades
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
50.00% WR (18 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Domination Domination
Electrocute Dark Harvest Hail of Blades
Cheap Shot Taste of Blood Sudden Impact
Zombie Ward Ghost Poro Eyeball Collection
Treasure Hunter Relentless Hunter Ultimate Hunter
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
66.67% WR (15 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Domination Domination
Electrocute Dark Harvest Hail of Blades
Cheap Shot Taste of Blood Sudden Impact
Zombie Ward Ghost Poro Eyeball Collection
Treasure Hunter Relentless Hunter Ultimate Hunter
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
33.33% WR (3 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Domination Domination
Electrocute Dark Harvest Hail of Blades
Cheap Shot Taste of Blood Sudden Impact
Zombie Ward Ghost Poro Eyeball Collection
Treasure Hunter Relentless Hunter Ultimate Hunter
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
100.00% WR (2 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Domination Domination
Electrocute Dark Harvest Hail of Blades
Cheap Shot Taste of Blood Sudden Impact
Zombie Ward Ghost Poro Eyeball Collection
Treasure Hunter Relentless Hunter Ultimate Hunter
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
0.00% WR (2 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Domination Domination
Electrocute Dark Harvest Hail of Blades
Cheap Shot Taste of Blood Sudden Impact
Zombie Ward Ghost Poro Eyeball Collection
Treasure Hunter Relentless Hunter Ultimate Hunter
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
100.00% WR (2 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
100.00% WR (2 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
50.00% WR (2 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
50.00% WR (2 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE
50.00% WR (2 Matches)
Resolve Resolve
Grasp of the Undying Aftershock Guardian
Demolish Font of Life Shield Bash
Conditioning Second Wind Bone Plating
Overgrowth Revitalize Unflinching
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE