Cassiopeia build for Mid Patch 14.23

Detail build guide Cassiopeia build or position Mid with the highest win rate. Runes, items, and skill build guide in Patch 14.23.
Cassiopeia
Cassiopeia the Serpent's Embrace
Serpentine Grace Noxious Blast Q Miasma W Twin Fang E Petrifying Gaze R
B Win rate 50.47% Pick rate 2.85% Ban rate 2.33% KDA 2.05
76% 18%

Cassiopeia runes

51.05% WR (7,959 Matches)
Precision Precision
Press the Attack Lethal Tempo Fleet Footwork Conqueror
Absorb Life Triumph Presence of Mind
Legend: Alacrity Legend: Haste Legend: Bloodline
Coup de Grace Cut Down Last Stand
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE

Cassiopeia Summoner spells

Flash Teleport
50.96% WR (9,817 Matches)

Cassiopeia item build

Starter items

Health Potion Health Potion Tear of the Goddess
51.20% WR (8,623 Matches)

Boots

Core items

Tear of the Goddess Rod of Ages Seraph's Embrace Rylai's Crystal Scepter
56.25% WR (3,026 Matches)

Cassiopeia skill order

Skill Priority

Twin Fang E Noxious Blast Q Miasma W
57.56% WR (7,969 Matches)

Skill Path

Noxious Blast Q
Noxious Blast
2 8 10 12 13
Miasma W
Miasma
3 14 15
Twin Fang E
Twin Fang
1 4 5 7 9
Petrifying Gaze R
Petrifying Gaze
6 11
Serpentine Grace P
Serpentine Grace

Cassiopeia Toughest Matchups

Heimerdinger
Heimerdinger 35.14% 37 Matches
Lissandra
Lissandra 35.59% 59 Matches
Hwei
Hwei 37.58% 157 Matches
Ekko
Ekko 43.27% 104 Matches
Lux
Lux 43.42% 228 Matches
Vladimir
Vladimir 44.59% 74 Matches
Naafiri
Naafiri 45.28% 53 Matches

Cassiopeia Easy to fight general

Azir
Azir 65.85% 41 Matches
Smolder
Smolder 63.27% 98 Matches
LeBlanc
LeBlanc 62.62% 107 Matches
Qiyana
Qiyana 61.54% 65 Matches
Viktor
Viktor 60.56% 71 Matches
Brand
Brand 60.00% 65 Matches
Yasuo
Yasuo 58.03% 305 Matches

Cassiopeia combos

Basic QAEEAEEAE
Medium R + F
Medium QEWEEERQEE
Expert QAEWEERFQEEE
Cassiopeia combos
Basic QAEEAEEAE
Medium R + F
Medium QEWEEERQEE
Expert QAEWEERFQEEE