Cassiopeia build for Mid Patch 14.22

Detail build guide Cassiopeia build or position Mid with the highest win rate. Runes, items, and skill build guide in Patch 14.22.
Cassiopeia
Cassiopeia the Serpent's Embrace
Serpentine Grace Noxious Blast Q Miasma W Twin Fang E Petrifying Gaze R
B Win rate 53.15% Pick rate 2.51% Ban rate 1.04% KDA 2.04
70% 20%

Cassiopeia runes

53.81% WR (1,457 Matches)
Precision Precision
Press the Attack Lethal Tempo Fleet Footwork Conqueror
Absorb Life Triumph Presence of Mind
Legend: Alacrity Legend: Haste Legend: Bloodline
Coup de Grace Cut Down Last Stand
Sorcery Sorcery
Summon Aery Arcane Comet Phase Rush
Nullifying Orb Manaflow Band Nimbus Cloak
Transcendence Celerity Absolute Focus
Scorch Waterwalking Gathering Storm
DEFENSE FLEX FLEX OFFENSE OFFENSE OFFENSE FLEX DEFENSE DEFENSE

Cassiopeia Summoner spells

Flash Teleport
53.79% WR (1,820 Matches)

Cassiopeia item build

Starter items

Health Potion Health Potion Tear of the Goddess
52.55% WR (1,313 Matches)

Boots

Core items

Tear of the Goddess Rod of Ages Seraph's Embrace Rylai's Crystal Scepter
55.38% WR (390 Matches)

Cassiopeia skill order

Skill Priority

Twin Fang E Noxious Blast Q Miasma W
58.91% WR (1,436 Matches)

Skill Path

Noxious Blast Q
Noxious Blast
2 8 10 12 13
Miasma W
Miasma
3 14 15
Twin Fang E
Twin Fang
1 4 5 7 9
Petrifying Gaze R
Petrifying Gaze
6 11
Serpentine Grace P
Serpentine Grace

Cassiopeia Toughest Matchups

Malzahar
Malzahar 37.84% 37 Matches
LeBlanc
LeBlanc 41.46% 41 Matches
Lux
Lux 43.75% 48 Matches
Kassadin
Kassadin 43.90% 41 Matches
Yone
Yone 44.64% 56 Matches
Hwei
Hwei 46.77% 62 Matches
Galio
Galio 48.15% 54 Matches

Cassiopeia Easy to fight general

Swain
Swain 62.50% 40 Matches
Zed
Zed 61.82% 55 Matches
Ahri
Ahri 57.69% 130 Matches
Orianna
Orianna 55.36% 56 Matches

Cassiopeia combos

Basic QAEEAEEAE
Medium R + F
Medium QEWEEERQEE
Expert QAEWEERFQEEE
Cassiopeia combos
Basic QAEEAEEAE
Medium R + F
Medium QEWEEERQEE
Expert QAEWEERFQEEE